High Shear Mixer Granulator for wet granulation process | STE Tecpharm
Granulation refers to the process in which primary dust particles are made to adhere to form larger entities of multiple particles called granules.
In this process of wet granulation, the granules are formed by adding an agglutinative solution.
The granulation solution contains a solvent or carrier material that must be volatile so that it can be removed by drying and not being toxic. Typical fluids include water, ethanol, and isopropanol alone or in combination. The liquid solution can be aqueous or solvent-based. Aqueous solutions have the advantage of being safer to treat than other solvents.
The granulation process combines one or more dust particles and forms a granule that will allow the formation of tablets within the required limits. In this way a predictable and repeatable process is possible and quality tablets can be produced using the STE TECPHARM technology.

The High Shear Mixer Granulator is designed to optimize the wet granulation process. Used to turn a fine-powder heterogeneous mixture into a uniform granulation, with increased particle size and higher density, offering proper flow and compactness properties, in a short time process and with repeatability.

Innovative high-quality equipment certified by accredited entities.


Fully designed and built in Europe following regulatory requirements and the GMP´s normative.
Bottom impeller and side chopper to guarantee the intensive mixing in a very short time period. Control of end point by time or by Torque.
In-wall design to be integrated in the clean room.
Standard equipment with capacities ranging from 25 L to 1.400 L. [Other dimensions on request].
Equipped with PLC + HMI for the control of the equipment in manual and automatic mode, with recipe editing.
Automatic impeller lift during cleaning phase.
Working platform adapted to the client room.


Binder reactor with peristaltic pump
Heating/cooling jacket
ATEX version
Product automatic charge and discharge by vacuum
Integrated wet conic mill calibrator
Automatic cleaning system (WIP)
Batch report
21CFR part 11 compliance module
Explosion proof 12 bar
Containment execution (until OEB 5)
Dust free loading system


STE TECPHARM offers all range of services from installation “turnkey concept” in the client facilities, start-up, qualification, training, and production support.

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