STE TECPHARM closes the contract for the manufacture of an OPTIMA tablet coater with a major German pharmaceutical company. The machine will be located in a subsidiary factory in Chile.
The requested equipment is a tablet coating machine with our patented OPTIMA technology. It is based on the perforated pan system, with a variable capacity of between 30Kg and 300Kg. Our patented system detects the volume of product introduced into the drum and automatically adjusts all process parameters for optimal coating:
– Position of spray nozzles.
– The applied liquid flow
– The inlet and exhaust air flow and temperature.
The equipment meets all the requirements of GMP regulations and the high quality standards of our customers and is adapted to comply with the ATEX zone 2/22 regulations.
STE Tecpharm wins the contract to manufacture a complete granulation line and a pharmaceutical tablet coating machine. The customer is a Hungarian pharmaceutical company specialized in drug development research. From raw material to finished product, this company participates in every step of the drug development process.
The tablet coater is a film coating equipment based on perforated pan technology. Its high technology allows automatic flow adjustment control, thus avoiding humidity, saving coating and optimizing the duration of the process.
The complete wet granulation line integrates all the production process options in a single frame and in a single control panel:
■ Mixing and Granulation: High Shear Mixer Granulator.
■ Drying: Fluidized Bed Dryer.
■ Calibration: Conical and cylindrical mill calibrators.
It minimizes the requested space in the cleanroom, reduces the risks of cross-contamination and provides maximum versatility for process development and scalability studies.
The High Shear Mixer Granulator has been designed to optimize the wet granulation process, transforming a heterogeneous mixture of fine powder into a uniform granulation, with particle size and a higher density, offering an appropriate flow and optimum compactness, inside of a process of short duration and repetition.
In the Fluidized Bed Dryer, the drying process is carried out to reduce the humidity in the granule. Hot air is introduced through a vacuum generated inside the equipment. The wet solids rise from the bottom and are suspended in a current of air, remaining in a fluidized state. The heat transfer and the low humidity of the air in direct contact with the wet granule allow the evaporation of the water or solvents, reducing their humidity.
All loading, product transfer between machines and final unloading is done by vacuum, avoiding product loss and minimizing the risk of cross-contamination.
All STE Tecpharm machines are innovative, high-quality equipment certified by accredited entities, fully designed and built in Europe according to legal requirements and Pharmaceutical Good Manufacturing Practice (GMP) standards.
STE Tecpharm introduces a new coating system called OPTIMA COATING SYSTEM. This perforated drum technology increases the batch size range from 10% to 100% and optimizes the parameter adjustment automatically.
On May 14th, 15th and 16th, STE opened its doors to a selection of customers interested in this new totally safe coating technology, designed in a way that the operator does not have to manipulate the equipment.
Among many of the advantages offered by the TP R OPTIMA are:
• Maximum flexibility batch range • Automatic adjustment depending on the level of charge • Arm driven by 2 motors • Automatic flaps to regulate exhaust air • In wall design
More than 50 clients from all over the world visited the STE facilities in Barcelona and have had the opportunity to see the new coating system working at full capacity. During the day two tests were carried out, one with 30KG of product (oblong tablets), and one of 300KG, so customers have witnessed live the flexibility of the TP R OPTIMA to cover batch sizes with weighings in the same equipment so different. All the tests have been successful! Obtaining a very good valuation by the clients.
In this way, STE Tecpharm completes its range of TP R products (COATERS) offering the highest quality and versatility in the world of solid coating.
STE Tecpharm signs the contract for the manufacture of a new OPTIMA tablet coater with a pharmaceutical company in Algeria. The customer is specialized in the production of generic drugs and has highly valued the variable production capacity of the OPTIMA tablet coating machine. Thanks to our equipment they will avoid the unproductive time of the drum exchange in other equipment, ensuring that the entire process of adapting the production capacity will be carried out fully automatically, without manual intervention by an operator and ensuring the highest quality of the final coating.
The OPTIMA coater is a perforated coating pan for tablets and pellets, suitable for aqueous and organic coatings, specially designed for the pharmaceutical industry.
It uses a patented technology that increases the batch range from 10% to 100% and optimizes parameter adjustment fully automatically. Its high technology allows automatic flow adjustment control, thus avoiding humidity, saving coating and optimizing the duration of the process.
The OPTIMA tablet coating machine controls each critical variable that is decisive for dynamic balance, such as:
■ The applied liquid flow.
■ Inlet airflow.
■ Outlet airflow.
■ Inlet and outlet air temperature.
■ The temperature of the tablets during the process.
■ The turning speed of the drum.
STE TECPHARM offers a full range of services, from “turnkey” concept installation at customer sites, to installation, qualification, training and production support.
This pharmaceutical company is dedicated to the manufacture and marketing of branded products of different pharmaceutical specialties and quality generics that are distributed with great success in the private and institutional market.
The complete installation consists of various pieces of equipment that cover different manufacturing processes for pharmaceutical granules and tablets:
STE Tecpharm delivers a new tablet coater with a perforated pan to an important Moroccan pharmaceutical laboratory, specialized in the development and manufacture of solid dosage forms that include effervescent tablets, oral disintegration tablets, and water-soluble granules.
The manufactured equipment has a working capacity of 150Kg per batch.
The system is controlled from a touch screen located on the front of the device, which allows manual or automatic operation (Touch Screen Panel + PLC + SIEMENS Industrial PC).
KEY FEATURES
■ Mobile coating arm for easy adjustment and maintenance.
■ Schlick guns to ensure perfect spraying.
■ Automatic download device.
It incorporates a WIP automatic washing system.
The equipment has been certified in accordance with the ATEX standard for the 2GD zone.
