STE Tecpharm completes the delivery of a complete wet granulation line for a pilot plant for the production of solid pharmaceutical forms, located in Spain.
The granulation line consists of different equipment, integrated into a single frame and managed from within the same control panel.
– 50L High-Shear Granulator.
– Calibrator mill for sieving the wet granule.
– Fluidized Bed Dryer 60L.
– Calibrator mill for sieving the dry granule.
– Fully automated loading, transport and unloading systems to avoid cross-contamination and ensuring optimal product transfer.
Once installed in the cleanroom, this set minimizes the space required and provides maximum versatility for development studies and process scalability.
STE Tecpharm delivers a full range of laboratory process equipment for the production of solid dosage forms to a Mexican engineering company specialized in the design and management of pharmaceutical projects. The set consists of various pieces of equipment in its laboratory version used for the development and research of new products.
– Laboratory High Shear Granulator.
– Laboratory Fluidized Bed Dryer.
– Laboratory Mill Calibrator.
– Laboratory Solid Mixer.
– Laboratory Tablet Coater.
They are equipped with a technology that easily allows changing to pilot scale. And also provides useful information for industrial batches.
LAB HIGH SHEAR MIXER GRANULATOR
The Lab Scale High Shear Mixer Granulator has been designed to turn a fine-powder heterogeneous mixture into a uniform granulation, with increased particle size and higher density.
It has 3 interchangeable bowls of 2, 5 and 10 liters.
Equipped with Siemens PLC and touch panel, It allows us to optimize the process and take relevant parameters: Mixing speed, Binding liquid flow, Dispersion of droplets size, and Granulation endpoint by Time or by Torque.
LABORATORY FLUIDIZED BED DRYER
Lab Scale Fluidized Bed Dryer designed for 3 different laboratory processes: Drying of wet granulate, Top drive granulation, Bottom spray coating for micro granules.
It disposes of 2 interchangeable recipients: 4,5 L and 9 L capacity.
Allows setting up specific drying programs for each product, which are executed from the operator touch panel, through necessary commands and controllers, achieving that in the process development and program set-up we can eliminate characteristic problems, such as Formation of air channels, Lack of uniformity in the drying process, Localized overheating of the granulation, and Attrition of the granulation as it dries.
LABORATORY MILL CALIBRATOR
Equipped with an electronic speed variator, this equipment is intended to reduce the size of dry and wet granules and to prepare raw materials of actives and excipients.
LABORATORY SOLID MIXER
The Laboratory Mixer has been designed to perform a mixing process for solids and powders with different types of containers.
This model has been designed considering the three main mixing variables determining a mixture: equipment geometry (container), loading level of the equipment, and mixing speed.
It allows the exchange of recipients of different geometries, such as Double cone, Bin, “V” Shape, and Drum.
LABORATORY TABLET COATER
Laboratory Tablet Coater with perforated coating pan designed to produce the film coating of tablets or pellets, suitable in aqueous and organic coatings.
The standard equipment is suitable to work with interchangeable drums from 0,5 to 2 Kg.
The Laboratory Tablet Coater controls each critical variable which is decisive for the dynamic equilibrium, such as Applied liquid flow, Inlet airflow, Exhaust airflow, Inlet and exit air temperature, Tablet temperature during the process, and Turning the speed of the pan drum.
Laboratory High Shear Granulator
Laboratory Fluidized Bed Dryer
Laboratory Mill Calibrator
Laboratory Solid Mixer
Laboratory Tablet Coater